Seiji Ito Selected Research

UBP296

6/2013

The action site of the synthetic kainoid (2S,3R,4R)-3-carboxymethyl-4-(4-methylphenylthio)pyrrolidine-2-carboxylic acid (PSPA-4), an analogue of Japanese mushroom poison acromelic acid, for allodynia (tactile pain).

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Seiji Ito Research Topics

Disease

104	Stomach Neoplasms (Stomach Cancer) 01/2024 - 01/2003
60	Neoplasms (Cancer) 01/2024 - 01/2002
34	Pain (Aches) 10/2023 - 01/2002
25	Hyperalgesia 10/2023 - 01/2002
21	Neoplasm Metastasis (Metastasis) 01/2024 - 01/2002
21	Neuralgia (Stump Neuralgia) 12/2023 - 04/2003
15	Carcinoma (Carcinomatosis) 04/2024 - 01/2002
8	Rectal Neoplasms (Rectal Cancer) 11/2023 - 06/2013
7	Adenocarcinoma 01/2024 - 07/2007
7	Lymphatic Metastasis 01/2024 - 01/2005
6	Pathologic Constriction (Stenosis) 11/2023 - 12/2015
6	Inflammation (Inflammations) 01/2016 - 01/2002
5	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 09/2002
5	Esophageal Neoplasms (Esophageal Cancer) 09/2023 - 02/2018
5	Peripheral Nerve Injuries 01/2017 - 11/2004
5	Peritoneal Neoplasms 09/2010 - 09/2004
5	Wounds and Injuries (Trauma) 01/2010 - 02/2008
4	Postoperative Pain 10/2020 - 10/2004
4	Carcinogenesis 01/2020 - 11/2002
4	Cecal Neoplasms 01/2018 - 12/2015
4	Neoplasm Micrometastasis 01/2012 - 01/2003
4	Gyrate Atrophy 03/2011 - 11/2003
3	Hemorrhage 11/2023 - 02/2020
3	Fistula 08/2022 - 01/2015
3	Colonic Neoplasms (Colon Cancer) 08/2022 - 12/2015
3	Anastomotic Leak 01/2022 - 08/2018
3	Neutropenia 01/2019 - 03/2017
3	Margins of Excision 12/2013 - 01/2006
3	Ascites 11/2009 - 01/2003
2	Fibrosis (Cirrhosis) 03/2024 - 02/2008

Drug/Important Bio-Agent (IBA)

15	Messenger RNA (mRNA)IBA 01/2016 - 01/2002
13	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2023 - 07/2003
12	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2003
11	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2014 - 06/2002
10	Paclitaxel (Taxol)FDA LinkGeneric 11/2021 - 10/2003
10	N-Methylaspartate (NMDA)IBA 09/2016 - 06/2004
8	Carcinoembryonic AntigenIBA 01/2023 - 01/2002
7	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 04/2010
7	NociceptinIBA 01/2018 - 10/2002
7	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 07/2007 - 01/2002
6	S-1 plus cisplatinIBA 01/2024 - 04/2010
6	Docetaxel (Taxotere)FDA Link 01/2020 - 01/2012
6	ProstaglandinsIBA 06/2008 - 07/2003
5	Dinoprostone (PGE2)FDA Link 01/2016 - 06/2004
5	acromelic acid AIBA 08/2015 - 06/2004
5	Analgesics (Analgesic Drugs)IBA 06/2012 - 04/2003
4	Glycoproteins (Glycoprotein)IBA 10/2023 - 07/2003
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 08/2022 - 01/2017
4	Fluorouracil (Carac)FDA LinkGeneric 08/2022 - 01/2003
4	Formaldehyde (Formol)FDA Link 01/2020 - 10/2002
4	AcidsIBA 01/2020 - 06/2004
4	NeuropeptidesIBA 01/2018 - 02/2006
4	nocistatinIBA 01/2018 - 03/2012
4	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 08/2015 - 09/2005
4	Glutamate Receptors (Glutamate Receptor)IBA 08/2015 - 06/2008
4	Therapeutic UsesIBA 01/2014 - 01/2005
4	OrnithineIBA 03/2011 - 11/2003
4	Retinal Pigments (Pigments, Visual)IBA 03/2011 - 11/2003
4	Transaminases (Aminotransferases)IBA 03/2011 - 11/2003
4	Indomethacin (Indometacin)FDA LinkGeneric 02/2011 - 07/2003
4	Nitric Oxide Synthase (NO Synthase)IBA 02/2011 - 09/2005
4	CytokinesIBA 02/2008 - 01/2004
3	Biomarkers (Surrogate Marker)IBA 02/2024 - 12/2012
3	LigandsIBA 10/2023 - 11/2008
3	CarbohydratesIBA 01/2023 - 06/2002
3	Tumor Biomarkers (Tumor Markers)IBA 01/2023 - 11/2002
3	AntigensIBA 01/2023 - 10/2009
3	ORALIT (ORS)IBA 09/2022 - 07/2013
3	Irinotecan (Camptosar)FDA LinkGeneric 08/2022 - 06/2011
3	AcetaldehydeIBA 01/2020 - 07/2013
3	Phosphotransferases (Kinase)IBA 01/2018 - 09/2005
3	Protein Isoforms (Isoforms)IBA 01/2018 - 11/2006
3	Phenylalanine (L-Phenylalanine)FDA Link 10/2016 - 09/2010
3	CarrageenanIBA 01/2016 - 01/2002
3	Freund's AdjuvantIBA 01/2016 - 06/2008
3	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 04/2015 - 06/2004
3	Dihydrotachysterol (AT 10)IBA 06/2013 - 10/2002
3	PoisonsIBA 06/2013 - 06/2004
3	Prostaglandins EIBA 02/2011 - 06/2004
3	NADPH Dehydrogenase (Dehydrogenase, NADP)IBA 12/2007 - 11/2004
3	Prostaglandin E Receptors (Prostaglandin E Receptor)IBA 02/2006 - 07/2003
3	N- (4- amino- 2- methylquinolin- 6- yl)- 2- (4- ethylphenoxymethyl)benzamideIBA 02/2006 - 10/2002

Therapy/Procedure

51	Gastrectomy 01/2024 - 06/2004
30	Drug Therapy (Chemotherapy) 02/2024 - 10/2005
20	Lymph Node Excision (Lymph Node Dissection) 01/2023 - 06/2004
19	Adjuvant Chemotherapy 03/2020 - 11/2008
15	Therapeutics 02/2024 - 10/2003
12	Neoadjuvant Therapy 01/2024 - 04/2010
9	Operative Surgical Procedures 11/2023 - 09/2002
8	Esophagectomy 09/2023 - 02/2015
6	Spinal Injections 10/2012 - 08/2004
5	Pelvic Exenteration 11/2023 - 08/2019
5	Pancreaticoduodenectomy 11/2021 - 03/2004
5	Oral Administration 01/2019 - 01/2003
4	Ileostomy 02/2024 - 07/2021
4	Urinary Diversion (Ileal Conduit) 11/2023 - 08/2019
4	Splenectomy 01/2023 - 01/2017
4	Colectomy 08/2022 - 11/2013
4	Laparotomy 01/2017 - 01/2002
3	Proctectomy 01/2022 - 08/2019